A tension arises between the human being and the world that is. Always, the formulation as an intensional act, is of overmining and undermining. Thinking too much of things toward a great overarching explanation, or thinking too little, into the minutiae of pieces and more pieces, as those might explain.
In particular to the object that is the subject, this tension is how knowledge coordinates with other objects.
Less how subjective knowledge is involved with objective knowledge (modern), knowledge itself, as a thing that arises in the universe, concerns orientation over coordination. That is, relationship and expansion in contrast to distillation and reduction. In a universe where Objects arise in relation to other objects, subjective knowledge becomes a manner to make notice of epistemological orientation, rather than the only envelope in which knowledge is able to arise.
The modern episteme is coordinated by differences in power, such that every human being arises as a hole in the universe, devoid of an actual body beyond a correlational Ideal (politics), and at no time able to appreciate the it’s true arrival in the universe itself.
Over and underdetermination are religious epistemological compensations by which the subject is asserted over all knowable things.